September 17, 2024 5:03 PM
Contact HSA
  • Professor Laila Jafri
  • +92-51-9522290-4 |
  • Ground Floor

Dr. Laila Jafri

Associate professor

Discipline

Life Sciences

Life Sciences

Publications

  • Khan, Fasiha Fayyaz, Rafia Ahsan, Atif Jamal, Laila Jafri, Rehana Rani, Samreen Saleem, Muhammad Adeel Javed, Kashif Sarfraz Abbasi, Samea Khan, and Muhammad Zakria. “Incidence and Molecular Characterization of Citrus Bacterial Canker Disease in Pakistan.” Journal of Plant and Environment 5, no. 2 (2023): 81-87.
  • Mahnoor Rizwan, Abdul Ahad, Sadia Aziz, Nazir Ahmed Lone, Tabasum Naz, Muhammad Bilal Khan, Laila Jafri, Liaqat Ali. A Study on Prevalence and Molecular Characterization of Spike Protein of SARS-COV 2 in Pakistan. Life and Science. 2023; 4(4): 458-468. doi: http://doi.org/10.37185/LnS.1.1.400.
  • Kainat Shafique, Aftab Farrukh, Tariq Mahmood Ali , Sumera Qasim, Laila Jafri, Hisham S. M. Abd-Rabboh, Murefah mana AL-Anazy, and Saima Kalsoom. Designing Click One-Pot Synthesis and Antidiabetic Studies of 1,2,3-Triazole Derivatives .2023. Molecules2023,28,3104. https:// doi.org/10.3390/molecules28073104 .
  • Nazia, Saadat Majeed, Batool Fatima, Bahareh Shirinfar, Dilshad Hussain, Laila Jafri, Nisar Ahmed, Sayed Tayyab Raza Naqvi Asghar Javeed, Rahat Nawaz. Cost-Effective Fabrication, Antibacterial Application and Cell Viability Studies of Modified Nonwoven Cotton Fabric. 2022. Scientific reports. 12:2493.IF. 4.996
  • Nosheen Akhtar , Sumra Wajid Abbasi , SaminaRubnawaz, LailaJafri. Proteomic profiling the molecular signatures of plectranthoic acid in prostate cancercells. Journal of Proteomics, Volume 246, 30 August 2021, 104311. IF. 3.855
  • Hafiz Syed Tanzeem-ul-Haq , Bilal Rasool , Syed Ehtisham-ul-Haque , Sadia Saif , Sadia Zafar , Tahira Younis, Imran Akhtar, Laila Jafri , Naeem Iqbal , Nasir Masood, Karolina Lewin ́ska and Muhammad Iqbal. 2021. Chitosan with Bentonite and Biochar in Ni-Affected Soil Reduces Grain Ni Concentrations, Improves Soil Enzymes and Grain Quality in Lentil. Minerals, 11, 11. IF. 2.989.
  • Awais Qarni, Motsim Billah, Khadim Hussain, Sabir Hussain Shah,
  • Waqas Ahmed, SADIA ALAM, Aftab Ahmed Sheikh, Laila Jafri, Asia Munir, Kouser Majeed Malik, Naeem Khan.2021. Isolation and Characterization of Phosphate Solubilizing Microbes from Rock Phosphate Mines and their Potential Effect for Sustainable Agriculture. Sustainability-1102001. IF.3.889
  • Bushra Rafique , Kainat Shafique , Sabahat Hamid , Saima Kalsoom ,Muhammad Hashim , Bushra Mirza , Laila Jafri & Mudassir Iqbal Novel Copper Complexes of Metronidazole and Metronidazole Benzoate: Synthesis, Characterization, Biological and Computational studies. Journal of Biomolecular Structure & Dynamics. Decision on Manuscript ID TBSD-2020-2021. IF. 5.235
  • Waleed Javed Hashmi, Hammad Ismail, Laila Jafri and Bushra Mirza. 2020.Ethnoparmacological activity of Hedera nepalensis K. Koch extracts and lupeol against alloxan-induced type I diabetes. Brazilian Journal of Pharmaceutical Sciences. http://dx.doi.org/10.1590/s2175-97902019000318406. Accepted. IF. 1.214
  • Tahira Younis, Faiza Jabeen, Laila Jafri, Azhar Rasul, Maleeha Manzoor, Mussarat Shaheen, Ammara Riaz. 2019. Protective potential of Fraxinus xanthoxyloides ethyl acetate fraction against CCl4- induced oxidative stress in cardiac tissue of rat. RA-ART-10-2019-008729.R1. Royal Society of Chemistry Advances. Accepted. RSC Adv., 2020, 10, 10221–10231 IF. 4.036
  • Tanveer Ahmed, Zunaira Raiz, Laila Jafri, Rashid Mahmood, Ihsan ul Haq, Leng Chee Chang5and Bushra Mirza .2019. Inhibition of mouse embryonic stem cell proliferation and induction of differentiation by natural products isolated from rhazya stricta decne. Pakistan Journal of pharmaceutical sciences. Vol.32, No.4(Suppl), July 2019, pp.1885-1891 .IF. 0.863.
  • Bilal Ahmad, Arshad Islam, Arif Khan, Mubarak Ali Khan, Ihsan-ul- Haq, Laila Jafri, Mansoor Ahmad, Shaila Mehwish, Ajmal Khan, Nazif Ullah. 2019. Comprehensive investigations on anti-leishmanial potentials of Euphorbia wallichii root extract and its effects on membrane permeability and apoptosis. Comparative Immunology, Microbiology and Infectious Diseases Volume 64, June 2019, Pages 138-145. IF. 2.729
  • Nosheen Akhtar, Laila Jafri, Brian D Green, Saima Kalsoom, Bushra Mirza. A Multi-Mode Commercially Relevant Bioactive Agent Isolated from Ficus Microcarpa L. Fill. With Therapeutic Potential for Type 2 Diabetes Mellitus. 2018. Front Pharmacol.. Manuscript ID: 382772. Accepted. IF 5.988.
  • Tahira Younis, Azhar Rasul, Faiza Jabeen, Ghulam Hussain, Javaria Altaf, Laila Jafri, Rehana Rani, Muhammad Rashid Khan, Iqra Sarfraz and Muhammad Ali. 2018. Ameliorating role of methanolic leaves extract of Fraxinus xanthoxyloides against CCl4-challanged nephrotoxicity in rats. Pakistan journal of Pharmaceutical Sciences, 31 (4):1474-1484. IF.0.863
  • Imran Khan, M.M.R. Chowdhury, Seok-Hwan Song, Ayman Mesalam, Shimin Zhang, Atif Ali Khan Khalil, Eun-Hee Jung, Ju-Boong Kim, Laila Jafri, Bushra Mirza, Il-Keun Kong. 2018. Lupeol supplementation improves the developmental competence of bovine embryos in vitro. Theriogenology 107 203-210. IF. 2.923.
  • Hammad Ismail, Ammara Rasheed, Ihsan Ul Haq, Laila jafri, Nazif Ullah, Erum Dilshad, Moniba Sajid and Bushra Mirza. 2017. Five indigenous plants of Pakistan with anti-nociceptive, anti-inflammatory, anti-depressant and anti-coagulant properties in Sprague Dawley rats. Evidence-Based Complementary and Alternative Medicine. IF. 2.650. https://doi.org/10.1155/2017/7849501
  • Laila Jafri, Samreen Saleem, Danielle Calderwood, Anna Gillespie, Bushra Mirza, Brian D Green.2016. Novel TGR5 agonists stimulating biosynthesis and secretion of glucagon-like peptide-1 (GLP-1). Peptides 78 (2016) 51–58. IF. 3.867
  • Laila Jafri, Samreen Saleem, Tamara P. Kondrytuk, Ihsan-ul-Haq, Nazif ullah, John M. Pezzuto and Bushra Mirza. 2016. Hedera nepalensis: a novel source of natural cancer chemopreventive and anticancerous compounds. Phytotherapy Research. 2016, 30(3):447-453. IF. 6.388
  • Nazif Ullah, Akhtar Nadhman, Shaila Mahvish, Sumaira Siddiq, Laila Jafri, Muhammad Hamayun. 2016. Plants as Antileishmanial Agents: Current Scenario”. Phytotherapy Research. DOI: 10.1002/ptr.5710. IF.6.388.
  • Laila Jafri, Samreen Saleem, Ihsan-ul-Haq, Nazif Ullah and Bushra Mirza. 2014. In vitro assessment of antioxidant potential and determination of polyphenolic compounds of Hedera nepalensis K. Koch. Arabian journal of Chemistry. 10.109[16/j.arabjc.2014.05.002. 6.212
  • Laila Jafri, Samreen Saleem, Ihsan ul Haq, Leng Chee Chang, Danielle Calderwood, Brian D Green, Bushra Mirza. 2014. Plants Fagonia cretica and Hedera nepalensis contain natural compounds with potent dipeptidyl peptidase-4 (DPP-4) inhibitory activity. Journal of Ethnopharmacology  156:26–32. IF. 5.195
  • Laila Jafri, Farzana Latif Ansari, Maryam Jamil, Saima Kalsoom, Sana Khurram, And Bushra Mirza. 2012. Microwave Assisted Synthesis And Bioevaluation of Some Semicarbazones. Chemical Biology & Drug Design. 79: 950–959.IF.2.873
  • A Iftakhar, IJ Hasan, M Sarfraz, L Jafri, MA Ashraf. 2016. Nephroprotective Effect of the Leaves of Aloe barbadensis (Aloe Vera) against Toxicity Induced by Diclofenac Sodium in Albino Rabbits. West Indian Med J. 462–7 .64(5). DOI: 7727/wimj.2016.052.IF 0.206.
  • Sara Ishaq, Laila Jafri. Biomedical Importance of Cocoa (Theobroma cacao): Significance and Potential for the Maintenance of Human Health. Matrix Science Pharma (MSP). 1(1) (2017) 01-05 .
  • Kainaat William, Laila Jafri. (2015). Mesquite (Prosopis juliflora): Livestock Grazing, Its Toxicity and Management. Journal of Bioresource Management 2 (2): 7. ISSN: 2309-385.
  • Amjad Hameed, Laila Jafri and Muneer A. Sheikh. “Effect of thiourea on proteins, catalase, guiacol-peroxidase and protease activities in wheat leaves under H2O2 induced oxidative stress.” (2013) Iranian J. Plant Physiol Vol:4(1): pp:857-864.

Health Care Associated Infections (HCAIs) a New Threat for World; U-Turn from Recovery to Death. Ayesha Noor, Ali Raza Ishaq, Laila Jafri, Faiza Jabeen, Rehana Rani, Bushra Hafeez Kiani, Nosheen Akhtar, Zeeshan Javed, Tahira Younis and Fatima Jalal. 2021. DOI: http://dx.doi.org/10.5772/intechopen.97193.

INTERNATIONAL CONFERENCE PRESENTATIONS

  • Oral presentation at 2nd International and 3rd National Conference on “Recent Advances in Drug Discovery and Development” (IRAD3)”. 15th- 16th, 2023. Institute of Molecular Biology and Biotechnology (IMBB)/ Center for Research in Molecular Medicine (CRiMM). The University of Lahore, Lahore, Punjab, Pakistan.
  • Oral presentation “International Conference on Food & Applied Sciences (ICFAS 2023)” at SBBU Shringal, Upper Dir KPK.
  • Attended workshop on “Food Safety and Hazard Analysis Critical Control Points for Protection of Public Health” at Quaid-i-Azam University, Islamabad June 23, 2022.
  • Attended “1st International Conference on Genomics and Animal Gut Microbes” on June 22, 2022, NARC, Islamabad.
  • Oral presentation at “1st International Conference on “Recent Advances in Drug Discovery and Development (2nd RAD3)”. March 24th- 25th, 2022. Institute of Molecular Biology and Biotechnology (IMBB)/ Center for Research in Molecular Medicine (CRiMM). The University of Lahore, Lahore, Punjab, Pakistan.
  • Participated in an international conference on “Changing Climate and Dengue Fever in the Era of CIVID-19 (09 & 10th February 2022 at Comsats Islamabad.
  • Attended “4th International Conference on Applied Zoology (ICAZ 2021) on 24th and 25th November 2021 at Quaid I Azam university Islamabad.
  • Participated as a Guest speaker in the online webinar arranged by BIG BIO on the topic “Girls & Women in Science; Challenges & Opportunities in Developing World” on Thursday, February 11, 2021.
  • Scientific committee judge at “1st International Conference on Recent Updates in Biotechnology” Held on October 16-19, 2019, organized by Department of Biotechnology, Abdul Wali Khan University, Mardan, KP, Pakistan.
  • Oral presentation in “1st International conference Advances in Drug Discovery & Development. Department of Biochemistry, Abdul Wali Khan University Mardan, jointly organized by PARC, Venue, NARC, Islamabad, 3-5 Jan, 2018.
  • Laila Jafri, Tehmina Mujahid, Evaluation Of cytotoxic and biological activities of ethnomedicinal plant Tamarix aphylla(L) Karst. Oral presentation at “The 4th International Conference on Biological and Computer Sciences (C-BICS 2016), Capital University of Science and Technology (CUST), Islamabad, 17th December 2016.
  • Laila Jafri, Samreen Saleem, Ihsan-ul-Haq, Nazif Ullah and Bushra Mirza. In vitro assessment of antioxidant potential and determination of polyphenolic compounds of Hedera nepalensis K. Koch. Poster presented at “The Society for General Microbiology. Irish Division Autumn Meeting. Gut microbes – friend, or foe? University of Ulster, Coleraine”. Thurs 29th – Fri 30th August 2013.

sNATIONAL CONFERENCES PRESENTATIONS

  • Attended “Advances in Nuclear Medicine and its Applications”, 19-20 September 2023 at COMSTECH Secretariat in Islamabad.
  • Oral presentation at “2nd National Conference on Bioactivity of Phytochemicals” held on 13-15 November 2018 at the University of Lahore, Lahore.
  • Attended hands-on training workshop of Flow cytometry held by Alpha Gnomics, Islamabad on 1-2 November 2017.
  • Invited Speaker at “1st Three Days National Conference On Bioactivity Of Phytochemicals” held on October 04-06, 2017 in University of Lahore, Lahore.
  • Attended “Basic Bioinformatics Workshop on April 19th -21st, 2016. At Institute of Molecular Biology and Biotechnology Bahauddin Zakariya University, Multan.
  • Frontier in Molecular Biology and Biotechnology work shop from 28th March to 30th March 2010.
  • Advances in Genetic Engineering of Plants 20th December to 22nd December 2011.

POSTER PRESENTATIONS

  • Laila Jafri, Samreen Saleem, Ihsan-ul-Haq, Munazza Ihtisham, Sara Sarwar, Ammara Rasheed, Nazif Ullah, Maryam Jamil and Bushra Mirza. Biological evaluation, isolation, and purification of bioactive compounds from selected medicinal plants of Pakistan. Poster presented in “National Conference on Trends in Biochemistry and Molecular Biology” on 21st February 2012.

Research Area

1-Exploring Nature's Pharmacy: Unraveling Anticancer and Antidiabetic Potentials of Bioactive Compounds: 2-Probing the Microbial Universe: Isolation, Characterization, and Exploring the Biological Potential of Probiotics for Health Innovations. 3- Unraveling the Threads of Resistance: Comprehensive Detection of Multidrug Resistance in Pathogens through Phenotypic and Genotypic Approaches. 4-Telomere Length Dynamics: Unraveling the Link Between Telomeres and Diverse Diseases for Precision Health. 5- Innovative Solutions for Bacterial Identification: Cost-Effective RNA Extraction, RNA Visualization Kit, and Modified String Test (Patent Filed).
  • FRSPH Royal Society of Public health, UK
  • FRCP Edin Royal College of Physicians Edinburgh, UK
  • PhD Liverpool School of Tropical Medicine, University of Liverpool, UK
  • MPH Ecole de Santé Publique, Université Henri Poincare, Nancy, France
  • MBBS Rawalpindi Medical College, Punjab University, Lahore

Education

PhD

(Biochemistry)

Quaid-i-Azam University Islamabad, Pakistan

September 2010-April 2015

M.Phil   

(Biochemistry)

Quaid-i-Azam University Islamabad, Pakistan

2006-2008

Master of Biochemistry

University of Agriculture Faisalabad, Pakistan

2003-2005

Research & Publications

BACKGROUNDTeaching Experience

  • Currently serving Assiociate Professor of Department of Life Sciences, Health Services Academy, Islamabad, Pakistan from Januray 2024-till to date.
  • Currently serving as HOD/Assistant Professor of Department of Life Sciences, Abasyn University Islamabad Campus, Islamabad, Pakistan from September 2018 -Januray 2024.

 

  • Launched several BS programs in AUIC, BS Medical Lab Technology, BS Biochemistry, BS Radiology Technology, Bs Human Nutrition and Dietetics, BS Prosthetics and Orthotics, and M-Phil Biochemistry.
  • Established Outcome Based Education System (OBE) in BS microbiology (BSMB) and BS Medical Lab Technology (BS-MLT) program. Developed Course Learning Outcomes (CLOs) of all courses and Program learning Outcomes (PLOs) of BSMB and BSMLT programs.
  • September 2018 till 2021 Assistant Professor (Visiting) Biochemistry Department, Quaid-i-Azam University Islamabad, Pakistan. Courses taught to M.Phil, M.Sc., BS
  • November 2016 till April 2018, Assistant Professor (Visiting) Biochemistry Department, BZU, Multan. Pakistan. Courses taught to Mphil, MS.c, BS
  • November 2015 -November 2016, Assistant Professor (IPFP) Biochemistry Department, BZU, Multan. Pakistan. Courses taught to Mphil, MS.c, BS
  • November 2014 till February 2015 Senior Research Officer in Biological Resource Center (BRC), Islamabad. Pakistan
  • July 2013 to January 2014: visiting research fellow at Advanced ASSET Centre, Institute for Global Food Security, School of Biological Sciences, Queens University Belfast, David Keir Building, Stranmillis Road, Belfast BT9 5AG, Northern Ireland, UK
  • 2011-2014: PhD. Fellow at Plant Molecular Biology Lab, Quaid-i-Azam University Islamabad Pakistan.
  • 2010-2011. Research associate in HEC funded project HEC Research Project No. 20-1417/R&D/09, PI Dr. Bushra Mirza, Department of Biochemistry, Quaid-i-Azam University Islamabad, Pakistan.
  • Aug 2008- March 2009: Lecturer (biology, chemistry) Islamabad College of management & commerce

_________________________________________________________________

MASTER TRAINER

  • Tehmina Mujahid. 2018“In Vitro Evaluation of Cytotoxic and Antioxidant Potential of Various Extracts of Tamarix Aphylla (L.) Karst and Salvadora oleiodes Decne.
  • Sehrish Hanif. 2018. Phytochemical Screening and Biological Activities of Cucumis Melo L. and Aerva Javanica (Burm.f.) Shult.
  • Mehmona Tariq. 2020. Apoptosis and Cell Viability Analysis of Peripheral Blood Mononuclear Cells Among Hepatitis B Virus Infected Individuals By Flow Cytometry.
  • Shajia khan. 2020. Estimation of Cell-Free Mitochondrial DNA Levels in The Serum of HBV infected Individuals.
  • Sumaira Sajjad. 2020. Circumsporozite Protein (Csp) Gene Based Population Genetics Study of Plasmodium Vivax Among Pakistani Population.
  • Nazneen shoukat. 2020. Polymophism analysis of Plasmodium vivax on the basis of Merosorozoite protein (MSP) Gene from Malarial patients.
  • Maryam Aziz 2022. Evaluation of cell free mitochondrial DNA levels in the serum of coronavirus infected individuals
  • Muhammad Ikram 2022. Genomic Sequencing based identification of beneficial bacteria from Capra aegagrus hirucs gut for their potential use as probiotics”.
  • Asma Arif 2022. Evaluation of in vitro adhesion capacity and cytotoxic activity of potential probiotic strains to Vero cells.
  • Sadia Faiz 2022. Isolation & Molecular Identification of Probiotic Bacterial Strains from Dairy & Non-Dairy Sources
  • Tahseen shoukat 2022. Molecular Characterization and Exploration of Soil Borne Fungi and its Impact on Host.
  • Mahnoor Rizwan 2022. Sero-prevalence and characterization of SARS-CoV2 in tertiary care hospital, Islamabad, Pakistan
  • Tabassum Naz. 2022. Identification and phylogenetic analysis of non-structural NS4/NS5 genes of Dengue serotype-2.
  • Muhmmad Ali.2022. Incidence of nosocomial respiratory tract infections in multi drug resistant tuberculosis (MDR-TB) patents of upper northern Punjab, Pakistan”.
  • Iqra Zahid .2023. Combined effects of plant growth promoting bacteria (PGPB) and nanoparticles on different varieties of Brassica oleracea.
  • Sana Arshad Abbasi .2023. “Development of gRNA/Cas9 Vector Construct for Rice (Oryza sativa L.) Dwarf 14 Gene and Optimization of Regeneration System in Basmati Rice Varieties”
  • Tooba Naseem .2023. “Enhanced Expression of Berberine Bridge Enzyme Gene in Escherichia coli and its Effect on Insects as Insecticidal Protein”
  • Sobia Ehsan .2023. “Determination of relative leukocytes telomere length by quantitative real-time polymerase chain reaction in diabetes mellitus patients in Pakistan: Rawalpindi, Islamabad “
  • Nadia Noreen .2023. “Evaluation Of Relative Telomere Length In Myocardial Infarction Patients From Rawalpindi Institute Of Cardiology, Pakistan”
  • Israr Ahmed .2023. “Comparative Evaluation of Colistin Resistance by Phenotypic and Genotypic Methods in Klebsiella Pneumoniae Isolates from Rawalpindi”

Expertise

  • Cell Membrane Signaling: Investigating the Interactions Between Natural Products and Cell Receptors, with a Focus on TGR5
  • Metabolomics and Phytochemical Analysis: Conducting Comprehensive Qualitative and Quantitative Analyses of Bioactive Natural Compounds in Plant Extracts
  • Isolation of Lead Compounds: Extracting Bioactive Molecules from Diverse Natural Sources, Including Plants, Marine Organisms, Fungi, and Microorganisms
  • Anticancer and Anti-diabetic Research: Uncovering Natural Products with Potential Therapeutic Applications for Cancer and Diabetes Treatment
  • Basic Molecular Biology Techniques: Proficiency in DNA Extraction, RNA Isolation, PCR, Cell Culture, ELISA, and Blotting
  • Chromatography Expertise: Utilizing Various Techniques, Such as Column Chromatography, Solid Phase Extraction, TLC, and HPLC
  • Bioassays: Employing a Range of Assays, Including Alpha-Glucosidase Inhibition, DPP4 Inhibition, Cancer Chemopreventive, Anti-Proliferative Assays, and In-Vivo Studies

CONFERENCES ORGANIZED (Focal Person):

  • Seminar “International Seminar on new Insight into Microbial and Biomedical Research” 2nd October 2021, Department of Life Sciences, Abasyn University Islamabad campus, Islamabad.
  • Seminar On” Flowcytometry: Principles and Applications” 2nd March, 2019. Department of Life Sciences, Abasyn University, Islamabad.
  • Hands-on Training Workshop on Next Generation Sequencing NGS Data Analysis. February 9-10,2019. Department of Life Sciences, Abasyn University, Islamabad.
  • RSC Pakistan 1st International Conference on Medicinal Chemistry and Drug Discovery” held on 18-19 October 2018 at COMSTECH, Islamabad, Pakistan.
  • National Conference on Trends in Biochemistry and Molecular Biology” 21st February 2012. Biochemistry Department. Quaid-i-Azam University, Islamabad.

Awards

  • Won HEC indigenous scholarship for 4 years PhD.
  • Got 6 months IRSIP scholarship (funded by HEC Pakistan) to visit Advanced ASSET Centre, Institute for Global Food Security, School of Biological Sciences, Queens University Belfast, David Keir Building, Stranmillis Road, Belfast BT9 5AG, Northern Ireland, UK as visiting research fellow.

PROJECTS

  • Title: An in vitro and in silico approach to cholinesterase inhibitory effects of selected medicinal plants extract, fractions, and their isolated compounds.

Year: 2016

Funding: SRGP of 500,000 PKR funded by HEC, Pakistan.

 

Social Media's